I'm Joe - a clinical researcher based in Birmingham, UK. My work focuses on appraising digital health technologies - things like predictive models, clinical calculators, and artificial intelligence.
Our team asks 3 main questions when we think about these technologies:
Do they work?
Are they safe?
Are particular groups at risk of harm if things go wrong?
Clinically I'm a speciality registrar in anaesthesia and intensive care medicine. I'm also a final year PhD student at the University of Birmingham. I'm a researcher for the STANDING Togther initative, co-organiser of The Alan Turing Institute's Clinical AI interest group, and co-lead for the Participatory Research theme at DSxHE.
References:
Challener DW, Prokop LJ, Abu-Saleh O. The Proliferation of Reports on Clinical Scoring Systems: Issues About Uptake and Clinical Utility. JAMA. 2019 Jun 25;321(24):2405–6. https://jamanetwork.com/journals/jama/fullarticle/2735005
Whitehead M. Equity in Medical Devices: Independent Review. Department of Health and Social Care. 2023. https://www.gov.uk/government/publications/equity-in-medical-devices-independent-review-final-report
Chen IY, Pierson E, Rose S, Joshi S, Ferryman K, Ghassemi M. Ethical Machine Learning in Healthcare. Annu Rev Biomed Data Sci. 2021 Jul;4:123–44. https://www.annualreviews.org/content/journals/10.1146/annurev-biodatasci-092820-114757
Paulus JK, Kent DM. Predictably unequal: understanding and addressing concerns that algorithmic clinical prediction may increase health disparities. npj Digit Med. 2020 Jul 30;3(1):1–8. https://www.nature.com/articles/s41746-020-0304-9
Cao J, Zhang X, Shahinian V, Yin H, Steffick D, Saran R, et al. Generalizability of an acute kidney injury prediction model across health systems. Nature Machine Intelligence. 2022 Dec;4(12):1121–9. https://www.nature.com/articles/s42256-022-00563-8
Obermeyer Z, Powers B, Vogeli C, Mullainathan S. Dissecting racial bias in an algorithm used to manage the health of populations. Science. 2019 Oct 25;366(6464):447–53. https://www.science.org/doi/10.1126/science.aax2342
Wong A, Otles E, Donnelly JP et al. External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients. JAMA Internal Medicine. 2021 Aug 1;181(8):1065–70. https://doi.org/10.1001/jamainternmed.2021.2626.
National Guideline Centre (UK). Evidence review for preoperative risk stratification tools: Perioperative care in adults [Internet]. London: National Institute for Health and Care Excellence (NICE); 2020. http://www.ncbi.nlm.nih.gov/books/NBK561975/